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NIANCE Epigen12™ Cell Renewal
Take one capsule in the morning to support your body’s circadian rhythm and fight jet lag. Powered by Epigen12™, it restores cellular vitality and enhances mitochondrial energy.
NIANCE GENR8® CLEANSE Biotic Supplement
A sophisticated detox formula designed to rebalance your gut-brain axis, support immunity, and ease digestion challenges from climate and food changes.
$ 513.00
Turning back the biological age clock by up to 12 years
EPIGEN12™ Cell Renewal, a groundbreaking innovation in the fight against aging that redefines what’s possible in cellular rejuvenation. Clinically proven to turn back your biological clock by up to 12 years, this advanced formula addresses 10 out of 14 hallmarks of aging at the deepest level. Powered by the next-generation EPIGEN12™ extract, it delivers unparalleled benefits by reducing epigenetic aging, preserving telomere length, and revitalizing mitochondrial energy production. Enhanced with Trans-Resveratrol for superior bioavailability and a synergistic combination of Nicotinamide Riboside and Niacinamide, EPIGEN12™ Cell Renewal optimizes DNA repair, boosts NAD+ levels, and defends against oxidative stress, setting a new benchmark for anti-aging innovation. Experience a revolutionary approach to longevity, vitality, and quality of life with this transformative product—designed for those who demand the ultimate in cellular health and rejuvenation.
Get the Inside, Out
NIANCE researchers travelled the globe to study centenarians and their lifestyle. They identified »gut health« as the key factor of our overall well-being, »healthy« aging and beauty. In other words: It shows on the outside when you feel good on the inside.
To improve well-being and beauty the unique formula of GENR8® CLEANSE enriches fresh and clean Swiss Glacier water with powerful natural ingredients from all over the world that help to remove environmental toxins from your body. The revolutionary FERNESSE™ biotechnology lifts bio-availabilty of essential ingredients to a new level by releasing their Triple-Biotic (pre-, pro- and post-biotics) properties. As a result your body can adsorb them within seconds rather than hours.
NIANCE Holistic Body Reset follows a precise 3-step physiological sequence designed to restore metabolic efficiency at its foundation:
STEP 1 — CLEAR
Restore Detoxification Capacity
The first step supports the body’s natural detoxification and elimination capacity, allowing metabolic regulation systems to function efficiently.
STEP 2 — UNBURDEN
Reduce Toxic & Metal Load
Once detoxification capacity is restored, the program supports the reduction of accumulated toxic and metal burden that silently disrupts metabolic and neurological balance.
STEP 3 — RE-IGNITE
Re-activate Energetic Metabolism
This step differentiates NIANCE Holistic Body Reset from conventional detox programs. It focuses on restoring how the body produces, distributes, and uses energy.
NIANCE Holistic Body Reset is built on a physiology-first systems logic:
This sequencing reflects how the human body actually works — and why single-step detox or fat-burn solutions often fail.
Micro-dosage biotech is a precision formulation approach where ingredients are used at low, targeted levels as part of a coordinated system design. It does not rely on high-dose single ingredients, but on synergy, timing, and intelligent composition to support how the body functions as an interconnected system.
Key Principles:
Precision Delivery System
FERNESSE™ biotechnology acts as the delivery engine behind the micro-dosage approach — ensuring that carefully selected ingredients are not only present, but effectively utilized by the body.
Rather than increasing quantity, FERNESSE™ focuses on how nutrients are delivered, absorbed, and coordinated within the system. By enhancing bioavailability and supporting coherent interaction between ingredients, it enables low-dose formulations to function with greater efficiency and precision.
Working in alignment with micro-dosage principles, FERNESSE™ ensures that each component contributes meaningfully within a connected biological network — supporting intelligent, system-wide performance rather than isolated effects.
Under high-fat nutritional conditions:
Reduced body weight gain compared to control. (p = 0.003)
Reduced adipose tissue accumulation
Reduced hepatic lipid deposition
No reduction in food intake
Increased oxygen consumption (VO2)
Enhanced thermogenesis
Increased fatty acid oxidation
Improved mitochondrial oxidative efficiency
Triglycerides improved vs. control (p = 0.0078)
LDL improved vs. control (p = 0.007)
No adverse HDL suppression
Reduced tissue lipid accumulation
Reduced vascular lipid deposition
Improved lipid utilization
Reduced inflammatory markers
1. Human Nutritional Intervention Data
Open Nutritional Study (n=35, 5 weeks)
12-Week Nutritional Study (n=104)
Double-Blind Subgroup (TG >1.7 mmol/L)
2. Detoxification & Physiological Recovery Observations
Post-Anesthesia Recovery (n=120)
Metabolic Balance Study (n=75)
Tobacco Withdrawal Support (n=180)
After 6 months:
Take 2 capsules daily —
1 capsule in the morning
1 capsule in the evening
At least 15 minutes after meals.
The optimal duration of NIANCE Holistic Body Reset depends on individual lifestyle, metabolic load, and health status. The following guidance is derived from available clinical and observational data and reflects a physiology-first approach, rather than a fixed one-size-fits-all cycle:
General metabolic reset / high-stress lifestyle: 28 days to 3 months
Smokers or individuals with higher toxic exposure: 3–6 months
Lipid imbalance or metabolic sluggishness: 3–6 months
Impaired liver markers or long-term metabolic burden: up to 12 months
For sustained metabolic resilience, the program may be repeated or continued under professional guidance.
| Unit | 30 Capsules |
|---|---|
| Packing | Bottle |
| Unit | 30 sachets |
|---|---|
| Packing | Liquid Sachet |
Biotin (Vitamin B8), Rapeseed Oil, Olive Oil, Grape Seed Oil, Evening Primrose Oil, Rock Samphire, Black Radish, Elderberry Bark, Pineapple, Apple, Chervil, Olive, Grapevine Seed, Gooseberry, Garlic Oil, Celery Seed, Rice, Lemon, Kelp, Plankton Extract, Bladderwrack, Dulse, Irish Moss, Yeast, Iceland Moss, White Lichen, Sea Lettuce, Shiitake Mushroom, Wood Ear Mushroom, Acerola, Grape Seed Extract (OPCs), Vitamin B12, Zinc, Magnesium, Iron, Sodium, Calcium, Vitamin A (Retinol), Vitamin B1 (Thiamin), Vitamin B3 (Niacinamide), Vitamin B6 (Pyridoxine), Vitamin B9 (Folic Acid), Vitamin C (Ascorbic acid), Vitamin E (Tocopherol), Vegetable Capsule.
Please keep the product in the dry and cool environment. Keep away from children.
| Reduces Toxic Load | Metabolic Reset | More Energy | Gut Health Support | Improves Nutrient Absorption
| Botox-Like Effect | Refined Pores | Improve Skin Firmness & density | Anti-aging
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