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Niance

Epigen12™ Cell Renewal

Facial serum to lift it up

EPIGEN12™ Cell Renewal is a revolutionary longevity supplement designed to turn back the biological clock by up to 12 years. With clinically proven results, this advanced formula tackles 9 hallmarks of aging, revitalizing your body at a cellular level for unparalleled rejuvenation and vitality.

Available on Preorder.
Next Shipment from 10th March 2025.
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$ 285.00 – $ 3'080.00

  • Available Worldwide
  • Free shipping

What It Is

EPIGEN12™ Cell Renewal, a groundbreaking innovation in the fight against aging that redefines what’s possible in cellular rejuvenation. Clinically proven to turn back your biological clock by up to 12 years, this advanced formula addresses 9 out of 12 hallmarks of aging at the deepest level. Powered by the next-generation EPIGEN12™ extract, it delivers unparalleled benefits by reducing epigenetic aging, preserving telomere length, and revitalizing mitochondrial energy production. Enhanced with Trans-Resveratrol for superior bioavailability and a synergistic combination of Nicotinamide Riboside and Niacinamide, EPIGEN12™ Cell Renewal optimizes DNA repair, boosts NAD+ levels, and defends against oxidative stress, setting a new benchmark for anti-aging innovation. Experience a revolutionary approach to longevity, vitality, and quality of life with this transformative product—designed for those who demand the ultimate in cellular health and rejuvenation.

Anti-aging | Anti-oxidant | Anti-pigmentation | Collagen synthesis | Firming | Hyaluronic acid synthesis | Lifting | Renewing | Wrinkle reduction

How It Works

NIANCE Premium Glacier Facial Serum is a highly concentrated skincare product that was specially designed to redefine and lift the contours of the face and to promote skin firmness. Our ground-breaking FERNESSE® biotechnology allowed us to transform natural active ingredients of this lifting serum into pre-absorbable and light textures. Grace to this innovation NIANCE Premium Glacier Facial Serum is absorbed immediately and can penetrate deep skin layers.

Benefits

  • A Botox-like effect
  • Activates the anti-aging function of cells and stimulates collagen synthesis
  • Leaves skin smooth and supple
  • Stimulates cell renewal and collagen production
  • Increases skin elasticity
  • Remodels the facial contour
  • Suitable for all skin types, even the most sensitive skin

How To Use

  1. After gentle skin cleansing (with NIANCE Cleansing Milk RELAX and NIANCE Facial Tonic REFRESH)
  2. Apply 2-3 drops of NIANCE Premium Glacier Facial Serum every morning and evening.
  3. Allow this lifting serum absorb and follow up with NIANCE Premium Glacier Facial Cream for maximum anti-aging and lifting result.
Video Thumbnail
Epigen12™ Cell Renewal Application Video

Science

SYN-AKE® is a new, highly effective active substance, based on the synthetically simulated toxin from the temple viper, acts against mimic wrinkles in a similar way to Botox, but is completely harmless.

Consumer Trials

84.85%

of the customers experienced a decrease in facial fine lines after using the product.

81.82%

of the customers experienced a reduction in facial wrinkles after using the product.

93.94%

of the customers experienced a reduction in facial skin laxity after using the product.

96.97%

of the customers experienced a decrease in dryness of facial skin after using the product.

87.88%

of the customers experienced a decrease in facial skin redness after using the product.

96.97%

of the customers experienced an improvement in the hydrating degree of facial skin after using the product.

100%

of the customers experienced an improvement in the moisturizing degree of facial skin after using the product.

100%

of the customers experienced an improvement in the smoothness degree of facial skin after using the product.

93.94%

of the customers experienced an improvement in the firmness degree of facial skin after using the product.

100%

of the customers experienced a moisturizing effect after using the product.

81.82%

of the customers experienced an anti-wrinkle effect after using the product.

90.91%

of the customers experienced a firming effect after using the product.

100%

of the customers experienced a soothing effect after using the product.

93.94%

of the customers believed that the product was mild and non-irritating.

100%

of the customers think this product is available for sensitive skin.

90.91%

of the customers were satisfied with the smell of the product.

96.97%

of the customers were satisfied with the absorption effect of the product.

96.97%

of the customers were satisfied with the texture of the product.

100%

of the customers were generally satisfied with the product.

* Based on a 4 weeks  of consumer use test.

See All Results...

Clinical Trials

The depth of the forehead wrinkles was reduced in the test by up to 52%*
The frequency of muscle contraction is reduced considerably after use:

  • By 36% after only 1 minute
  • By 82% after 2 hours
  • By 67% even after 2 days

After 28 days of application

Swiss Glacier Complex® - 4 X 4 BENEFITS

Swiss Glacier Complex® is the core revitalizing engine of NIANCE skincare products, composed of four (4) groups of potent active ingredients from the Alps, achieving four (4) comprehensive anti-aging effects: 24-hour long-lasting hydration and moisturizing, skin microbiome support, wrinkle reduction and prevention, and firming & lifting.

Swiss Glacier Complex®, the core engine and soul of Niance skincare products, is made up of 4 powerful fundamental elements – Swiss Apline glacier water, vitamin cocktail, complex of minerals and active substances from high Alpine plants. Swiss Glacier Complex® is like a stream of light poured into a bottle. It safeguards the well-being of the epidermis, stimulates cell renewal, delays the first signs of skin aging, and reactivates the skin’s own ability to regenerate and rejuvenate by stimulating the synthesis of collagen, hyaluronic acid and elastin. The skin becomes smooth, firm and youthful. Thanks to the proprietary FERNESSE™ biotechnology that transforms Edelweiss, Thymus Vulgaris, Gentiana Lutea Root, Buddleja Davidii and Borago Officinalis Seed oil by enzymatic activation, Swiss Glacier Complex® achieves the high performance of anti-aging but in an environmentally-friendly way, without the use of paraffins, parabens, mineral oils, sensitizers, microplastics, hormones and genetically modified ingredients. It is a vegan-friendly complex.

FERNESSE™ Biotechnology - The Triple-Biotics Power

The ground-breaking FERNESSE™ biotechnology of NIANCE is revolutionizing the concept of holistic anti-aging inside out, by releasing the full Triple-Biotics power (pre-, pro- and post-biotics) of active ingredients and drastically increase the bio-availability of nutrients. FERNESSE™ ensures our skincare and supplements deliver optimal results quickly and efficiently.

Key Ingredients​

Our Promises

Additional information

Unit

30 Capsules

Packing

Bottle

Aqua (water), Propylene Glycol, Pullulan, Algae Extract, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Glycerin, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Colostrum, Ethylhexylglycerin, Alcohol, Lecithin, Carbomer, Parfum, Thymus Vulgaris (thyme) Flower/leaf Extract, Buddleja Davidii Extract, Leontopodium Alpinum Extract, Gentiana Lutea Root Extract, Tocopheryl Acetate, Borago Officinalis Seed Oil, Caprylic/capric Triglyceride, Retinyl Palmitate, Ascorbyl Palmitate, Xanthan Gum, Lysine, Magnesium Chloride, Potassium Chloride, Aluminum Chloride, Zinc Chloride, Manganese Chloride, Sodium Chloride, Copper Sulfate, Gluconolactone, Phenethyl Alcohol, Calcium Gluconate, Ethylhexylglycerin, Sodium Levulinate, Sodium Hydroxide, Potassium Hydroxide, Citric Acid

Please keep the product in the dry and cool environment. Please finish using the product within 6 months after opening.

FAQ

Facial serum is a concentrated targeted product with a large amount of active ingredients. Due to the light texture, it is better absorbed into the skin and work more effectively on solving specific problems.

Apply NIANCE Premium Glacier Facial Serum to cleansed and toned skin. Since the facial serum is a rather concentrated product, only 2-3 drops of the product are enough. It is also very economical. After the serum, be sure to apply the cream to seal the product and get the maximum effect.

Facial serums and facial moisturizers help the skin in different ways. Cream is the basic daily care. Facial serum is a targeted product that can enhance the hydrating, soothing or anti-aging benefits of any skincare regimen. If we select the cream according to the type of skin, then when choosing a serum, you must first focus on the problems you want to cope with. For example, NIANCE Premium Glacier Facial Serum, is a global rejuvenating serum, that makes the skin tighter and firmer.

Skin care golden rule is to go from thinnest to thickest, with water-based products usually followed by cream or oil-based products. A facial serum won’t be able to penetrate the epidermis effectively if they must pass through a barrier created by a cream. So you should apply facial serum before your facial cream moisturizer.

Swiss Glacier Complex® could only appear in Switzerland. It is made up of 4 powerful fundamental elements – glacier water, vitamin cocktail, complex of minerals and active substances from high alpine plants. This is NIANCE know-how, a well-thought-out combination of ingredients that activates the skin cells and stimulates them to resist aging on their own. Swiss Glacier Complex® activates and stimulates the body’s natural anti-aging process resulting in skin that looks and feels healthier and younger, at every stage in life.

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4.89
9 reviews
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1
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Customer Image Gallery
  1. Anonymous
    As a 52-year-old business owner, my life often feels like it’s spent on planes or in boardrooms. Before starting NIANCE EPIGEN12™ Cell Renewal, my DNA bioage test shocked me—it was 63. Over three months, with EPIGEN12™, improved diet, and regular exercise, my bioage reduced dramatically to 49! This transformation has encouraged me to continue taking EPIGEN12™ Cell Renewal and maintain a healthier lifestyle. I feel sharper, more energetic, and better equipped to handle my demanding schedule
    Switzerland
    6
  2. Olivia H.
    Being a full-time mom to four kids, I’m used to putting myself last. At 45, I thought I was aging ‘normally,’ but my bioage test showed I could do better. After three months of EPIGEN12™ Cell Renewal, my bioage reduced to 38! I feel like I’ve reclaimed my energy and zest for life, which means more quality time with my kids. I’m amazed at how much this product has helped me.
    Singapore
    5
  3. Anna L.
    As a 38-year-old working mom with two children, frequent cross-continental travel and poor sleep were taking a toll on me. Jet lag and exhaustion were constants in my life. Since starting EPIGEN12™ Cell Renewal, I’ve noticed a huge improvement in my sleep quality and energy levels. I feel more rested and capable of managing my busy schedule, even with frequent travel. It’s been a game-changer for my well-being.
    Zurich, Switzerland
    7
  4. Sarah L.
    I’m a 42-year-old entrepreneur constantly juggling work and family. After using EPIGEN12™ Cell Renewal for six months, my DNA bioage test revealed a reduction from 40 to 32 years—a stunning 8-year difference! Not only does my body feel younger, but my mind is sharper, and I’m full of energy every day.
    Zurich, Switzerland
    5
  5. Mark D.
    As a 50-year-old fitness coach, maintaining high energy levels is non-negotiable. Since starting EPIGEN12™, I’ve felt a significant improvement in my stamina and mood. My bioage test confirmed the change, showing my biological age at 38. I recommend this to anyone wanting to feel as vibrant as they did in their 30s!
    London, UK
    6
  6. Emily R.
    I’m a 35-year-old marketing professional, and sleep deprivation used to ruin my productivity. After three months of EPIGEN12™, my sleep quality has drastically improved. I wake up refreshed and focused. My bioage test also showed a reduction of 5 years, which was an added bonus!
    Geneva, Switzerland
    5
  7. Thomas W.
    At 63, I was looking for ways to maintain my vitality as I transition into retirement. EPIGEN12™ has been life-changing! My bioage test dropped from 60 to 48 years. My skin glows, and I feel like I’ve unlocked a new level of energy and confidence.
    Geneva, Switzerland
    8
  8. Patrick K.
    As a 49-year-old doctor, long hours had started taking a toll on my health. EPIGEN12™ has improved my recovery times and resilience. My DNA bioage test showed my biological age as 35—a testament to how this product supports me through a hectic lifestyle.
    Shanghai, China
    6
  9. Luca M.
    At 47, I noticed visible signs of aging and low energy. EPIGEN12™ has been a game-changer. Not only do I feel 10 years younger, but my bioage test revealed a 7-year reduction. It’s like my cells are rejuvenating every day. It fits perfectly into my routine as a finance executive.
    Lugano, Switzerland
    7

Niance

Epigen12™ Cell Renewal

$ 285.00 – $ 3'080.00

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CONSUMER USE TEST RESULT

Epigen12™ Cell Renewal

84.85%

of the customers experienced a decrease in facial fine lines after using the product.

81.82%

of the customers experienced a reduction in facial wrinkles after using the product.

93.94%

of the customers experienced a reduction in facial skin laxity after using the product.

96.97%

of the customers experienced a decrease in dryness of facial skin after using the product.

87.88%

of the customers experienced a decrease in facial skin redness after using the product.

96.97%

of the customers experienced an improvement in the hydrating degree of facial skin after using the product.

100%

of the customers experienced an improvement in the moisturizing degree of facial skin after using the product.

100%

of the customers experienced an improvement in the smoothness degree of facial skin after using the product.

93.94%

of the customers experienced an improvement in the firmness degree of facial skin after using the product.

100%

of the customers experienced a moisturizing effect after using the product.

81.82%

of the customers experienced an anti-wrinkle effect after using the product.

90.91%

of the customers experienced a firming effect after using the product.

100%

of the customers experienced a soothing effect after using the product.

93.94%

of the customers believed that the product was mild and non-irritating.

100%

of the customers think this product is available for sensitive skin.

90.91%

of the customers were satisfied with the smell of the product.

96.97%

of the customers were satisfied with the absorption effect of the product.

96.97%

of the customers were satisfied with the texture of the product.

100%

of the customers were generally satisfied with the product.

* Based on a 4 weeks  of consumer use test.