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Niance

Epigen12™ Cell Renewal

Get ready to glow

EPIGEN12™ Cell Renewal is a revolutionary longevity supplement designed to turn back the biological clock by up to 12 years. With clinically proven results, this advanced formula tackles 9 hallmarks of aging, revitalizing your body at a cellular level for unparalleled rejuvenation and vitality.

Available on Preorder.
Next Shipment from 10th March 2025.
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$ 285.00 – $ 3'080.00

  • Available Worldwide
  • Free shipping

What It Is

EPIGEN12™ Cell Renewal, a groundbreaking innovation in the fight against aging that redefines what’s possible in cellular rejuvenation. Clinically proven to turn back your biological clock by up to 12 years, this advanced formula addresses 9 out of 12 hallmarks of aging at the deepest level. Powered by the next-generation EPIGEN12™ extract, it delivers unparalleled benefits by reducing epigenetic aging, preserving telomere length, and revitalizing mitochondrial energy production. Enhanced with Trans-Resveratrol for superior bioavailability and a synergistic combination of Nicotinamide Riboside and Niacinamide, EPIGEN12™ Cell Renewal optimizes DNA repair, boosts NAD+ levels, and defends against oxidative stress, setting a new benchmark for anti-aging innovation. Experience a revolutionary approach to longevity, vitality, and quality of life with this transformative product—designed for those who demand the ultimate in cellular health and rejuvenation.

Acne-Prone | Anti-aging | Anti-oxidant | Collagen synthesis | Hyaluronic acid synthesis | Hydrating

How It Works

NIANCE Facial Tonic REFRESH contains highly-concentrated glacier water from the Swiss Alps, including valuable extracts from the Hyssop Plant. This toner stimulates cell renewal by neutralising and firming the skin for a radiating, fresh glow.

Benefits

  • Radiant, glowing skin
  • Refreshes instantly
  • Strengthens skin’s microbiome
  • Suitable for all skin types, even the most sensitive skin
  • Vegan

How To Use

  1. Spray the facial tonic onto a cotton pad.
  2. Gently pat the cotton pad onto the face, neck and cleavage area.
  3. Gently pat the face with hands to allow the facial tonic fully absorbed by the skin.

Alternatively, to revive tired skin just spray Facial Tonic REFRESH directly on your face. Then gently pat your face with your hands to allow the facial tonic to be fully absorbed by the skin..

Video Thumbnail
Epigen12™ Cell Renewal Application Video

Science

Saccharomyces Lysate Extract, created by a postbiotic fermentation technology, awakens the skin’s natural power to revive dull-looking skin.

Consumer Trials

100%

of customers experienced a reduction in facial fine lines after using the product.

100%

of customers noticed a reduction in facial wrinkles after using the product.

100%

of customers experienced a decrease in the dryness of their facial skin after using the product.

96.97%

of customers experienced a decrease in facial skin redness after using the product.

100%

of customers noticed a decrease in the oil secretion of their facial skin after using the product.

100%

of customers experienced an improvement in the hydrating degree of their facial skin after using the product.

100%

of customers noticed an improvement in the moisturizing degree of their facial skin after using the product.

100%

of customers experienced an improvement in the smoothness degree of their facial skin after using the product.

100%

of customers noticed a moisturizing effect of the product after use.

100%

of customers noticed an anti-wrinkle effect of the product after use.

100%

of customers noticed a soothing effect of the product after use.

100%

of customers noticed an oil control effect of the product after use.

100%

of customers believed that the product was mild and non-irritating.

100%

of customers thought that the product was suitable for sensitive skin.

100%

of customers were satisfied with the smell of the product.

100%

of customers were satisfied with the absorption effect of the product.

100%

of customers were satisfied with the texture of the product.

100%

of customers were generally satisfied with the product.

* Based on a 4 weeks  of consumer use test.

See All Results...

Clinical Trials

Boosted oxygen uptake dose-dependently by up to 750% compared to untreated control and increased cell turnover activity by up to 25% compared to untreated sites.

Swiss Glacier Complex® - 4 X 4 BENEFITS

Swiss Glacier Complex® is the core revitalizing engine of NIANCE skincare products, composed of four (4) groups of potent active ingredients from the Alps, achieving four (4) comprehensive anti-aging effects: 24-hour long-lasting hydration and moisturizing, skin microbiome support, wrinkle reduction and prevention, and firming & lifting.

Swiss Glacier Complex®, the core engine and soul of Niance skincare products, is made up of 4 powerful fundamental elements – Swiss Apline glacier water, vitamin cocktail, complex of minerals and active substances from high Alpine plants. Swiss Glacier Complex® is like a stream of light poured into a bottle. It safeguards the well-being of the epidermis, stimulates cell renewal, delays the first signs of skin aging, and reactivates the skin’s own ability to regenerate and rejuvenate by stimulating the synthesis of collagen, hyaluronic acid and elastin. The skin becomes smooth, firm and youthful. Thanks to the proprietary FERNESSE™ biotechnology that transforms Edelweiss, Thymus Vulgaris, Gentiana Lutea Root, Buddleja Davidii and Borago Officinalis Seed oil by enzymatic activation, Swiss Glacier Complex® achieves the high performance of anti-aging but in an environmentally-friendly way, without the use of paraffins, parabens, mineral oils, sensitizers, microplastics, hormones and genetically modified ingredients. It is a vegan-friendly complex.

FERNESSE™ Biotechnology - The Triple-Biotics Power

The ground-breaking FERNESSE™ biotechnology of NIANCE is revolutionizing the concept of holistic anti-aging inside out, by releasing the full Triple-Biotics power (pre-, pro- and post-biotics) of active ingredients and drastically increase the bio-availability of nutrients. FERNESSE™ ensures our skincare and supplements deliver optimal results quickly and efficiently.

Play Video

NIANCE Facial Tonic REFRESH uses the purest glacier water from the Matterhorn in Switzerland. It restores your skin microbiome and provides deep hydration. This tonic prepares your skin perfectly for the next steps in your skincare routine. Featuring the Swiss Glacier Complex® and Hyssop Plant Extract, it soothes and revitalizes, ensuring your skin feels fresh and balanced.

Dr. Patrick Schwarzentruber
Chairman of the Committee of Microbiological Experts (Member of the Board)
Switzerland

Key Ingredients​

Our Promises

Additional information

Unit

30 Capsules

Packing

Bottle

Aqua (water), Propanediol, Pentylene Glycol, Hyssopus Officinalis Extract, Decyl Glucoside, Disodium Cocoyl Glutamate, Saccharide Isomerate, Citric Acid, Sodium Citrate, Saccharomyces Lysate Extract, Glycerin, Phenoxyethanol, Alcohol, Lecithin, Proline, Parfum, Benzophenone-4, Thymus Vulgaris (thyme) Flower/leaf Extract, Buddleja Davidii Extract, Leontopodium Alpinum Extract, Gentiana Lutea Root Extract, Tocopheryl Acetate, Borago Officinalis Seed Oil, Caprylic/capric Triglyceride, Retinyl Palmitate, Ascorbyl Palmitate, Lysine, Magnesium Chloride, Potassium Chloride, Aluminum Chloride, Zinc Chloride, Manganese Chloride, Sodium Chloride, Copper Sulfate, Sodium Benzoate, Gluconolactone, Phenethyl Alcohol, Calcium Gluconate, Sodium Levulinate, Potassium Sorbate

Please keep the product in the dry and cool environment. Please finish using the product within 6 months after opening.

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4.89
9 reviews
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  1. Anonymous
    As a 52-year-old business owner, my life often feels like it’s spent on planes or in boardrooms. Before starting NIANCE EPIGEN12™ Cell Renewal, my DNA bioage test shocked me—it was 63. Over three months, with EPIGEN12™, improved diet, and regular exercise, my bioage reduced dramatically to 49! This transformation has encouraged me to continue taking EPIGEN12™ Cell Renewal and maintain a healthier lifestyle. I feel sharper, more energetic, and better equipped to handle my demanding schedule
    Switzerland
    6
  2. Olivia H.
    Being a full-time mom to four kids, I’m used to putting myself last. At 45, I thought I was aging ‘normally,’ but my bioage test showed I could do better. After three months of EPIGEN12™ Cell Renewal, my bioage reduced to 38! I feel like I’ve reclaimed my energy and zest for life, which means more quality time with my kids. I’m amazed at how much this product has helped me.
    Singapore
    5
  3. Anna L.
    As a 38-year-old working mom with two children, frequent cross-continental travel and poor sleep were taking a toll on me. Jet lag and exhaustion were constants in my life. Since starting EPIGEN12™ Cell Renewal, I’ve noticed a huge improvement in my sleep quality and energy levels. I feel more rested and capable of managing my busy schedule, even with frequent travel. It’s been a game-changer for my well-being.
    Zurich, Switzerland
    7
  4. Sarah L.
    I’m a 42-year-old entrepreneur constantly juggling work and family. After using EPIGEN12™ Cell Renewal for six months, my DNA bioage test revealed a reduction from 40 to 32 years—a stunning 8-year difference! Not only does my body feel younger, but my mind is sharper, and I’m full of energy every day.
    Zurich, Switzerland
    5
  5. Mark D.
    As a 50-year-old fitness coach, maintaining high energy levels is non-negotiable. Since starting EPIGEN12™, I’ve felt a significant improvement in my stamina and mood. My bioage test confirmed the change, showing my biological age at 38. I recommend this to anyone wanting to feel as vibrant as they did in their 30s!
    London, UK
    6
  6. Emily R.
    I’m a 35-year-old marketing professional, and sleep deprivation used to ruin my productivity. After three months of EPIGEN12™, my sleep quality has drastically improved. I wake up refreshed and focused. My bioage test also showed a reduction of 5 years, which was an added bonus!
    Geneva, Switzerland
    5
  7. Thomas W.
    At 63, I was looking for ways to maintain my vitality as I transition into retirement. EPIGEN12™ has been life-changing! My bioage test dropped from 60 to 48 years. My skin glows, and I feel like I’ve unlocked a new level of energy and confidence.
    Geneva, Switzerland
    8
  8. Patrick K.
    As a 49-year-old doctor, long hours had started taking a toll on my health. EPIGEN12™ has improved my recovery times and resilience. My DNA bioage test showed my biological age as 35—a testament to how this product supports me through a hectic lifestyle.
    Shanghai, China
    6
  9. Luca M.
    At 47, I noticed visible signs of aging and low energy. EPIGEN12™ has been a game-changer. Not only do I feel 10 years younger, but my bioage test revealed a 7-year reduction. It’s like my cells are rejuvenating every day. It fits perfectly into my routine as a finance executive.
    Lugano, Switzerland
    7

Niance

Epigen12™ Cell Renewal

$ 285.00 – $ 3'080.00

Order now
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CONSUMER USE TEST RESULT

Epigen12™ Cell Renewal

100%

of customers experienced a reduction in facial fine lines after using the product.

100%

of customers noticed a reduction in facial wrinkles after using the product.

100%

of customers experienced a decrease in the dryness of their facial skin after using the product.

96.97%

of customers experienced a decrease in facial skin redness after using the product.

100%

of customers noticed a decrease in the oil secretion of their facial skin after using the product.

100%

of customers experienced an improvement in the hydrating degree of their facial skin after using the product.

100%

of customers noticed an improvement in the moisturizing degree of their facial skin after using the product.

100%

of customers experienced an improvement in the smoothness degree of their facial skin after using the product.

100%

of customers noticed a moisturizing effect of the product after use.

100%

of customers noticed an anti-wrinkle effect of the product after use.

100%

of customers noticed a soothing effect of the product after use.

100%

of customers noticed an oil control effect of the product after use.

100%

of customers believed that the product was mild and non-irritating.

100%

of customers thought that the product was suitable for sensitive skin.

100%

of customers were satisfied with the smell of the product.

100%

of customers were satisfied with the absorption effect of the product.

100%

of customers were satisfied with the texture of the product.

100%

of customers were generally satisfied with the product.

* Based on a 4 weeks  of consumer use test.