In the competitive world of skincare, NIANCE has emerged as a leader by seamlessly blending nature and cutting-edge science. At the heart of this innovation is FERNESSE™, a groundbreaking biotechnology that elevates the efficacy of NIANCE products, ensuring deeper absorption and enhanced delivery of active ingredients into the skin. In this blog, we’ll dive into the science behind FERNESSE™, its unique mechanisms, and how it transforms skincare into a more potent and effective experience.

What is FERNESSE™ Biotechnology?

FERNESSE™ is a proprietary biotechnological process developed by NIANCE’s Swiss research team. The goal of this technology is to optimize the absorption and bioavailability of active ingredients. In skincare, the ability of ingredients to penetrate the skin barrier and reach deeper layers is crucial for delivering tangible results. Many skincare formulations, while rich in potent actives, fail to deliver their full potential due to the skin’s natural barrier functions.

FERNESSE™ is designed to overcome these limitations. By modifying the structure and behavior of active ingredients at a molecular level, FERNESSE™ enhances their ability to pass through the skin’s outer layers and reach the dermis, where many vital processes related to aging, hydration, and cell regeneration occur.

How Does FERNESSE™ Work?

FERNESSE™ releases the full Triple-Biotics power (pre-, pro- and post-biotics) of active ingredients and drastically increase the bio-availability of nutrients. FERNESSE™ ensures our skincare and supplements deliver optimal results quickly and efficiently. At its core, FERNESSE™ operates through two primary mechanisms: enzymatic activation et small-molecule delivery.

1. Enzymatic Activation of Ingredients

FERNESSE™ employs enzymatic activation to alter the structure of plant extracts and active compounds. Enzymes are biological catalysts that speed up chemical reactions in the body. In the FERNESSE™ process, enzymes are used to break down larger, less penetrative molecules into smaller, more bioavailable forms without compromising their potency.

This process is particularly effective when applied to plant-based ingredients, such as those found in NIANCE’s Complexe des Glaciers Suisses®, which contains alpine plant extracts like Edelweiss, Gentiana Lutea Root, and Buddleja Davidii. The enzymatic activation ensures that the beneficial compounds within these plants are more easily absorbed by the skin.

For example, when Edelweiss is enzymatically activated through FERNESSE™, its antioxidant properties are amplified, allowing it to better protect the skin from oxidative stress and environmental damage. Similarly, Gentiana Lutea Root, known for its anti-inflammatory properties, becomes more efficient in reducing redness and irritation.

2. Small-Molecule Delivery System

In addition to enzymatic activation, FERNESSE™ incorporates a small-molecule delivery system. This system is engineered to reduce the size of the active ingredients to ensure they can penetrate the skin barrier effectively. The skin’s barrier is highly selective, allowing only small molecules to pass through its tight junctions.

By reducing the molecular size of ingredients such as vitamin C, retinol (vitamin A), and collagen-boosting peptides, FERNESSE™ enhances their ability to reach deeper layers of the skin where collagen synthesis, cell regeneration, and melanin regulation take place.

For instance, ascorbic acid (vitamin C) is a key ingredient in many NIANCE products for its ability to brighten skin and reduce pigmentation. However, vitamin C in its natural form can be unstable and may struggle to penetrate the skin. FERNESSE™ stabilizes vitamin C and reduces its molecular size, making it more bioavailable and ensuring it reaches the dermis where it can effectively combat pigmentation and stimulate collagen production.

FERNESSE™ in Action: The Benefits

By leveraging both enzymatic activation and small-molecule technology, FERNESSE™ offers a range of benefits that elevate NIANCE products above conventional skincare solutions:

1. Enhanced Absorption and Penetration

FERNESSE™ ensures that active ingredients are delivered into the deeper layers of the skin where they can enact meaningful change. This enhanced absorption translates into faster and more visible results, whether it’s reducing wrinkles, improving skin texture, or evening out pigmentation.

2. Targeted Delivery of Active Ingredients

The small-molecule delivery system allows ingredients to be more precisely targeted to specific areas of the skin. For example, peptides known to stimulate collagen production can now reach the dermis more effectively, leading to firmer, more youthful skin.

3. Improved Efficacy of Plant-Based Extracts

FERNESSE™ amplifies the natural potency of plant-based ingredients, making them more effective in treating skin concerns like inflammation, oxidative stress, and environmental damage. By breaking down plant molecules into their most bioavailable forms, FERNESSE™ ensures that your skin can make full use of their benefits.

4. Stable and Potent Formulations

Ingredients that are traditionally unstable, such as vitamin C and retinol, are stabilized through the FERNESSE™ process. This not only improves their shelf life but also ensures that they remain potent and effective when applied to the skin.

Supporting Clinical Data

FERNESSE™ technology is backed by clinical studies demonstrating its efficacy in delivering skincare results. Products formulated with FERNESSE™ have shown measurable improvements in skin hydration, firmness, and the reduction of fine lines and pigmentation over a short period.

1. NIANCE Premium Glacier Facial Cream:

• Improved Hydration: Test subjects experienced a 48% increase in skin hydration after four weeks of consistent use.
• Reduction in Wrinkle Depth: The depth of forehead wrinkles was reduced by up to 52% after 28 days of application. The frequency of muscle contraction was also significantly reduced by:
  • 36% after just 1 minute
  • 82% after 2 hours
  • 67% even after 2 days.

2. Whitening Serum RADIANT:

• Skin Lightening Efficacy: Clinical trials revealed that the Whitening Serum RADIANT achieved 3x better skin-lightening results compared to traditional agents like ascorbyl glucoside, kojic acid, and Glycorrhyza glabra root extract.

3. NIANCE Whitening Mask NeuroRELAX:

• Reduction of Redness and Improved Luminosity: In just two weeks, users observed a significant reduction in redness (up to 19 times) and a 57% improvement in skin luminosity. After one month, users reported a more radiant complexion and an overall improvement in skin quality.

Conclusion

NIANCE’s FERNESSE™ biotechnology represents a significant advancement in skincare science. By enhancing the bioavailability and penetration of active ingredients, FERNESSE™ ensures that your skincare products work harder and deliver faster, more noticeable results. Whether it’s through enzymatic activation or small-molecule delivery, FERNESSE™ brings the best of nature and science together, offering a more efficient and effective approach to skincare.

With NIANCE and FERNESSE™, you’re not just treating your skin—you’re transforming it at the cellular level, ensuring long-lasting beauty and health from the inside out.